Why does one person gain weight differently than another? What molecular events dictate fat tissue function, and how can we use this information to narrow the gap between the lab bench and disease prevention?

Fat is an intelligent organ. Our fat tissue can be influenced by a myriad of different factors, and it can differ vastly from one person to the other, depending on things like genetics. One person with obesity might be predisposed to type 2 diabetes, but another might not.

We need an understanding of how these processes are regulated at the molecular level if we wish to develop better, personalised prevention and treatment strategies.

Listen as experts on the molecular regulation of fat tissue and the pharmaceutical industry discuss improving metabolic health by identifying genes essential for fat tissue function.

Episode info

Guests

• Alison Ludzki, Novo Nordisk postdoctoral fellow at Karolinska Institutet in Sweden.

• Mads Tang-Christensen, former Head of Obesity & Liver Disease Research at Novo Nordisk in Denmark.

Host

• Gretchen Repasky, Communications Director, Nordic EMBL Partnership for Molecular Medicine and University of Helsinki.

Transcript

Download transcript

Publisher

Danish Diabetes Academy

Producer

Kontekst & Lyd

Resource list

• Truth About Weight – What is Obesity?

• Mads Tang-Christensen: The brain science of obesity. TED

• Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin

• Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation

• Acute Aerobic Exercise Remodels the Adipose Tissue Progenitor Cell Phenotype in Obese Adults